Immune suppressive treatment in paediatric myocarditis: still awaiting the evidence.

نویسنده

  • M Burch
چکیده

Correspondence to: Dr Michael Burch, Great Ormond Street Hospital, London WC1N 3JH, UK; [email protected] . . . . . . . . . . . . . . . . . . . . . . . P aediatric and adult cardiological practices are dominated by (respectively) congenital and atheromatous heart disease. Some diseases are common to both specialities, an example being myocarditis. It is a paradox that a 15 year old child may be given potent immune suppressive treatment for myocarditis but a 16 year old on the adult cardiology ward with the same diagnosis will not. What is the evidence for this conundrum?

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Monocytic myeloid-derived suppressor cells from females, but not males, alleviate CVB3-induced myocarditis by increasing regulatory and CD4+IL-10+ T cells

Coxsackievirus group B type 3 (CVB3) is a common etiologic agent of viral myocarditis and often causes sexually dimorphic myocarditis with increased incidence and mortality in male. So far, the underlying mechanism for the high male prevalence is not well elucidated. In this study, we deciphered the role of myeloid-derived suppressor cells (MDSCs) in the gender bias in murine CVB3-induced myoca...

متن کامل

The role of extracorporeal mechanical assists ( ECLS et al . )

Extracorporeal mechanical assist earlier named extracorporeal circulation (ECC)) has evolved markedly over recent years. ECLS (extra corporeal life support) is employed for the management of life threatening heart or heart and lung failure, when no other treatment option is likely to be successful. Mostly it is instituted in an emergency or urgent situation after failure of other treatment moda...

متن کامل

Myocarditis in Paediatric Patients: Unveiling the Progression to Dilated Cardiomyopathy and Heart Failure

Myocarditis is a challenging and potentially life-threatening disease associated with high morbidity in some paediatric patients, due to its ability to present as an acute and fulminant disease and to ultimately progress to dilated cardiomyopathy. It has been described as an inflammatory disease of the myocardium caused by diverse aetiologies. Viral infection is the most frequent cause of myoca...

متن کامل

Paediatric Surgery: A Comprehensive Text For Africa [Chapter 14]

The last few decades have been marked by tremendous improvement in the successful performance of most paediatric surgical procedures. This improvement is in terms of both increased knowledge and skills of attending physicians and updated surgical equipment now available for a variety of procedures. This has resulted in a higher survival rate as well as a reduction in the associated risk. Despit...

متن کامل

Post-vaccination myositis and myocarditis in a previously healthy male

BACKGROUND The immunological literature has been redefining clinical phenomena as hypotheses emerge regarding causal links between triggers, immunologic manifestations, and their specific inflammatory cascades. Of late, autoimmune manifestations that appear to be caused by an external adjuvant have been grouped into a complex syndrome referred to as autoimmune/inflammatory syndrome induced by a...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Heart

دوره 90 10  شماره 

صفحات  -

تاریخ انتشار 2004